Drugs & Vitamins

Tarceva Active Ingredients: Erlotinib Representative Names: Tarceva Available Product Images: What are Erlotinib tablets? What should I tell my health care provider before I take this medicine? How should this medicine be used? What if I miss a dose? What drug(s) may interact with Erlotinib? What side effects may I notice from receiving Erlotinib? What should I watch for while taking Erlotinib? Where can I keep my medicine? What are Erlotinib tablets? (Back to top) ERLOTINIB (Tarceva™) targets a specific protein within cancer cells and stops the cancer cells from growing. Erlotinib is used to treat certain cancers including non-small cell lung cancer. This drug might be used to treat other cancers as well. Generic erlotinib tablets are not available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •liver disease •lung fibrosis •previous chemotherapy or radiation therapy •an unusual reaction to Erlotinib, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should this medicine be used? (Back to top) Take erlotinib tablets by mouth. Follow the directions on the prescription label. Take on an empty stomach at the same time each day between meals. It is important to take this drug 1 hour before or 2 hours after eating. Taking this drug with food may increase your chance of developing side effects. Do not take your medicine more often than directed. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) Take your missed dose as soon as you remember. If it is almost time for your next dose, take only that one, and skip your missed dose. Do not take extra or double doses. What drug(s) may interact with Erlotinib? (Back to top) •amiodarone •carbamazepine •antiviral medicines for the treatment of HIV or AIDS •bosentan •certain medicines for fungal infections (such as fluconazole, itraconazole, ketoconazole, or voriconazole) •certain medicines for high blood pressure •clarithromycin •erythromycin •grapefruit juice •medicines for depression •non-steroidal anti-inflammatory drugs (NSAIDs such as ibuprofen or naproxen) •phenobarbital •phenytoin •propafenone •rifabutin •rifampin •risperidone •St. John's wort or any herbal products containing St. John's wort •warfarin Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving Erlotinib? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •bleeding •chest pain •difficulty seeing, speaking, or standing, or weakness in an arm or leg •eye irritation •eye pain •fever •mouth sores •problems related to breathing including shortness of breath or cough •severe or persistent diarrhea, nausea, vomiting, or loss of appetite Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •decreased appetite •diarrhea •dry skin •itching •nausea, vomiting •skin rash, including acne •weakness •weight loss What should I watch for while taking Erlotinib? (Back to top) Visit your prescriber or health care professional for checks on your progress. You will need to have regular blood checks. The side effects of erlotinib may continue after your finish your treatment; report side effects promptly. If you experience severe or continuing diarrhea, nausea, decreased appetite, or vomiting, contact your health care provider. This medicine has been associated with severe lung side effects. Contact your health care provider if your breathing gets worse and/or you develop any new symptoms, such as a cough. There is a risk of birth defects if this medicine is given during pregnancy. Women should not become pregnant while taking this medicine. Adequate birth control methods should be used during treatment, and for at least two weeks after stopping treatment. Consult with your health care provider regarding appropriate options for birth control. Tell your doctor or health care professional if you smoke before you take this medicine. Also, tell your prescriber or health care professional if you plan to start or stop smoking. Where can I keep my medicine? (Back to top) Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15—30 degrees C (59—86 degrees F). Throw away any unused medicine after the expiration date on the label. Last Updated:08/07/2007 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.